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Proteogenomic approaches in non-small-cell lung cancerfor precision medicine
- POSTED DATE : 2024-11-07
- WRITER : 화학과
- HIT : 516
- DATE : 2024년 11월 7일(목) 오후 4시 30분
- PLACE : 330226호
많은 참여 부탁드립니다.
Proteogenomic approaches in non-small-cell lung cancerfor precision medicine
Name: Kwang Pyo Kim1,
Affiliations: Kyung Hee University1,
Addresses 1732 Deokyoung-daero, Yongin, Korea
Abstract: Non-small cell lung cancer (NSCLC) can be histologically divided into lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LSCC), though some tumors display ambiguous characteristics. Other pathophysiological and microenvironmental factors often play a significant role. In our study, we performed integrative multiomics analyses on a Korean NSCLC cohort alongside previous studies. This revealed five molecular subtypes, including a novel NSCLC subtype characterized by upregulated PI3K-Akt pathway activity, associated with high metastasis rates and poor survival outcomes across NSCLC histologies. We developed a method to pinpoint driver genomic alterations, underscoring the crucial role of multiomics in tumor classification, diagnostic accuracy, and prognosis assessment. We will also explore the benefits and scientific significance of multi-omics integration in cancer research.
* 졸업논문 교과목 수강자 세미나 필수 참석 안내
석사, 석박통합, 박사과정이 수강하는 <졸업논문연구학점 1~6>수강자는 학과에서 개최하는 목요일 정규세미나에 반드시 참석해야함.
관련공지(https://chem.skku.edu/chem/News/notice.do?mode=view&articleNo=178815&article.offset=10&articleLimit=10)
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