Seminar 게시판읽기 ( Stickers and Spacers in Biomolecular Condensation : Who Are They ? )

Seminar

HOME
Board
Seminar

Seminar

Stickers and Spacers in Biomolecular Condensation: Who Are They?

POSTED DATE : 2024-11-15
WRITER : 화학과
HIT : 712

DATE : 2024년 11월 21일(목) 오후 4시 30분
PLACE : 330226호

화학과 세미나가 다음 주 목요일 (11월 21일) 오후 4시 30분에 개최됩니다.

많은 참여 부탁드립니다.

===================================================================

- 제목 : Stickers and Spacers in Biomolecular Condensation: Who Are They?

- 연사 : 최정모 교수(부산대 화학과)

- 일시 : 2024년 11월 21일(목) 오후 4시 30분

- 장소 : 화학관 2층 330226호실

===================================================================

Stickers and Spacers in Biomolecular Condensation: Who Are They?

Jeong-Mo Choi¹

¹Department of Chemistry, Pusan National University, Busan 46241, Republic of Korea

*E-mail: jmchoi@pusan.ac.kr

The stickers-and-spacers framework, proposed in 2018 (Wang et al., Cell 2018), provides insights into the collective behaviors of heteropolymers, particularly biomolecules such as proteins and nucleic acids. Inspired by the associative polymer theory, this model categorizes polymer constituents into two groups: those engaging in chain-chain interactions (stickers) and those that do not (spacers). The model has garnered significant interest due to its explanatory power regarding the role of intrinsically disordered proteins/regions (IDPs/IDRs) in biomolecular condensation. Notably, the existence of a hierarchy of stickers, based on their contributions to chain-chain interactions, has been suggested. However, the model has also sparked misunderstandings and critiques. In this presentation, I will elucidate the framework and its modifications and present recent findings that offer a non-canonical illustration of the stickers-and-spacers framework.

* 졸업논문 교과목 수강자 세미나 필수 참석 안내
석사, 석박통합, 박사과정이 수강하는 <졸업논문연구학점 1~6>수강자는 학과에서 개최하는 목요일 정규세미나에 반드시 참석해야함.

List