Seminar

Seminar

[세미나 공지] - 2014년 3월 21일(금)

  • POSTED DATE : 2014-03-17
  • WRITER : 관리자
  • HIT : 2417
  • DATE : 2014-03-21
  • PLACE : 330226호실

3월 21일 금요일에 해외석학 특별초청세미나가 개최됩니다.

많은 참석 바랍니다.

 

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제  목 : Metal Cluster Catalyst for Transesterification and Amide Alcoholysis
 

연  사 : Prof.Kazushi Mashima(오사카 대학교)
 

일  시 : 2014년 3월 21일(금) 오후 4시 30분


장  소 : 화학관 세미나실 (330226호실)

 

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Metal Cluster Catalyst for Transesterification and Amide Alcoholysis

Kazushi Mashima

 

Department of Chemistry, Graduate School of Engineering Science,

Osaka University, Toyonaka, Osaka 560‑8531, Japan.

Email: mashima@chem.es.osaka-u.ac.jp

 

   The ester moiety represents one of the most ubiquitous functional groups in organic compounds, serving as both key intermediate and protecting group in organic transformations. Among various esterification reactions established so far, one of the most convenient synthetic methods is transesterification, in which methyl or ethyl esters react with various alcohols to give the corresponding esters in one step.  We developed -oxo-tetranuclear zinc cluster Zn4(OCOCF3)6O as an efficiently catalyst for transesterification, including chemoselective acylation of hydroxy group in the presence of aliphatic amino group, catalytic acetylation of alcohols and catalytic deacetylation of acetates. Because of mildness of the reaction conditions, these reactions have a high degree of functional-group tolerance. Recently, cobalt clusters mediate the same chemoselectivity for transesterification.  Amide bond formation and degradation are also discussed.