안녕하세요.

 

다음주 월요일(9월 21일) 세미나가 진행됩니다.

많은 참석 부탁드립니다.

 

감사합니다.

 

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제 목 : Rational Design of Metal Ligands and Chiral Sensors

연 사 : 김현우 교수님 (KAIST)

일 시 : 2015년 9월 21일 (월) 오후 4시 30분

장 소 : 화학관 1층 강의실 (330118호실)

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Rational Design of Metal Ligands and Chiral Sensors

 

Over the years, the increasing knowledge of transition metal catalysis has resulted in an enormous advances of green chemical technologies, as exemplified by such processes as C-H functionalization, direct cross coupling, and cascade or multicomponent reactions. The so-called privileged ligands have been reported to enhance the catalytic activity of various transition metals. The ultimate goal of my research is to develop another class of privileged ligands and transition-metal catalysts. During the last several years of research, we have observed the remarkable reactivity of 2,2’-dihydroxy benzophenone, which is based on a new phosphorus ligand (briphos) and chiral sensors. More importantly, in order to explain the observed electronic properties of briphos, we have proposed a new concept, geometric control, to modulate the ligand property in addition to conventional steric and electronic control. With this new concept and our own synthetic tool, we hope to develop a privileged ligand structure and explore transition metal catalysis to discover unseen reactivity and selectivity. Moreover, our recent progress on the development of chiral sensors will be introduced.

 

 

 

 

References:

(1) Lee, A.; Kim, H. J. Am. Chem.Soc. 2015, 137, 11250.

(2) Lee, A.; Ahn, S.; Kang, K.; Seo, M.-S.; Kim, Y.; Kim, W. Y.; Kim, H. Org. Lett.,2014, 16, 5490.

(3) Seo, M. S.; Lee, A.; Kim, H. Org. Lett., 2014, 16, 2950.

(4) Seo, M. S.; Kim, K.; Kim, H. Chem. Commun., 2013, 49, 11623 (Inside Cover)